(DELRAY BEACH, FL)– Florida Highway Patrol is working to determine the cause of the multi-vehicle accident that caused a tanker truck to explode, injuring 5 people and shutting down I-95 near Atlantic Avenue for hours.

The incident occurred at just before 1:15 PM Tuesday when witnesses say a northbound car collided with the fuel tanker, causing the truck to overturn and burst into flames.

Another northbound driver attempting to avoid the crash hit the median wall, knocking a lamppost onto a pair of vehicles in the southbound lanes of 95.

Smoke from the fire could be seen for miles and multiple explosions were reported by witnesses.

A secondary fire started when burning fuel leaking from the tanker truck ran through a storm drain and onto the southbound shoulder of the interstate.

Firefighters from as far away as Broward County were brought into assist and the blaze eventually extinguished using a combination of water and foam.

Three of the accident victims were taken to Delray Medical Center and two others were airlifted to the burn unit at Jackson Memorial Hospital in Miami.

The interstate completely reopened to traffic just after 5:30 PM.